1-(Chloromethyl)-4-phenoxybenzene → 2-Methyl-4-(4-phenoxy-benzylsulfanyl)-phenoxyl-acetic acid

反応式

Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][CH:4]=1.C[O:17][C:18](=[O:29])[CH2:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([SH:27])=[CH:23][C:22]=1[CH3:28]>>[CH3:28][C:22]1[CH:23]=[C:24]([S:27][CH2:2][C:3]2[CH:8]=[CH:7][C:6]([O:9][C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[CH:5][CH:4]=2)[CH:25]=[CH:26][C:21]=1[O:20][CH2:19][C:18]([OH:29])=[O:17]

参加物

反応物 2

HCID 5209941-(Chloromethyl)-4-phenoxybenzene

HCID 20770797Methyl (2-methyl-4-sulfanylphenoxy)acetate

生成物 1

HCID 222800072-Methyl-4-(4-phenoxy-benzylsulfanyl)-phenoxyl-acetic acid

実験手順

The title compound was prepared in the manner analogous to Example 1F with 1-chloromethyl-4-phenoxy-benzene and 2C. MS m/z 321 (M-methylacetate).

出典と根拠

ORDレコード: ord-8cee5cad7ded46e29fe8dcd55cf9b684
出典データセット: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06964983B2

反応ノート

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