(8-Mercapto-chroman-5-yloxy)-acetic acid methyl ester → {8-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-5-yloxy}-acetic Acid
反応式
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[O:5][N:4]=1.C[O:19][C:20](=[O:34])[CH2:21][O:22][C:23]1[CH:32]=[CH:31][C:30]([SH:33])=[C:29]2[C:24]=1[CH2:25][CH2:26][CH2:27][O:28]2>>[F:15][C:14]([F:17])([F:16])[C:11]1[CH:12]=[CH:13][C:8]([C:6]2[O:5][N:4]=[C:3]([CH2:2][S:33][C:30]3[CH:31]=[CH:32][C:23]([O:22][CH2:21][C:20]([OH:34])=[O:19])=[C:24]4[C:29]=3[O:28][CH2:27][CH2:26][CH2:25]4)[CH:7]=2)=[CH:9][CH:10]=1参加物
3
実験手順
The title compound was prepared in the manner analogous to Example 1F using 42C and (8-mercapto-chroman-5-yloxy)-acetic acid methyl ester. mp 112-113° C.; MS m/z 480 (M+1).
出典と根拠
- ORDレコード
- ord-1c801abf11e14c2db47536224dd4dc41
- 出典データセット
- uspto-grants-2005_11