Hydrochloric Acid → HCID 9928554、化合物

HRID 1064076ノート

反応式

HRID 1064076 の反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([N:14]2[C:18]([C:19]3[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=3)=[C:17]([C:25]3[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][CH:26]=3)[C:16](=[O:32])[NH:15]2)[CH2:10][CH2:9]1)=O)(C)(C)C.Cl>CCOCC.O1CCOCC1>[Cl:31][C:28]1[CH:29]=[CH:30][C:25]([C:17]2[C:16](=[O:32])[NH:15][N:14]([CH:11]3[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]3)[C:18]=2[C:19]2[CH:20]=[CH:21][N:22]=[CH:23][CH:24]=2)=[CH:26][CH:27]=1

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 69357048HCID 69357048、化合物

生成物 1

HCID 9928554HCID 9928554、化合物

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 312751,4-Dioxane溶媒

実験手順

To a solution of 4-[4-(4-Chloro-phenyl)-3-oxo-5-pyridin-4-yl-2,3-dihydro-pyrazol-1-yl]-piperidine-1-carboxylic acid tert-butyl ester 200 mg in flask was added HCl in ether and dioxane. After 2.25 hours, the solvent was evaporated under reduced pressure to afford the title compound as yellow oil. MS (ES+): 355 (M+H)+; (ES−): 353 (M−H).

後処理

  1. customthe solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-f3227960537d4a8588a4dfe254704bf8
出典データセット
uspto-grants-2005_11
特許番号
US06967254B2

反応ノート

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