4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one → 4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-1,2-dihydro-pyrazol-3-one
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH:13]([C:14]3[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=3)[NH:12][NH:11][C:10]2=[O:20])[CH:5]=[CH:6][C:7]=1[Cl:8]>CO>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[C:10](=[O:20])[NH:11][NH:12][C:13]=2[C:14]2[CH:15]=[CH:16][N:17]=[CH:18][CH:19]=2)[CH:5]=[CH:6][C:7]=1[Cl:8]参加物
3
実験手順
The solution of 4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one 0.30 g, 20 mg Pd/C and 20 mL methanol was stirred at room temperature. Air was bubbled through for 2 hours. Filtered off the Pd/C catalyst, vacuumed down all solvent. The title compound was obtained as white solid 0.29 g. MS (ES+): 306 (M+H)+.
後処理
- customAir was bubbled through for 2 hours
- filtrationFiltered off the Pd/C catalyst
出典と根拠
- ORDレコード
- ord-e2745fa2c552426ba70f5438b53e9be8
- 出典データセット
- uspto-grants-2005_11
- 特許番号
- US06967254B2
反応ノート
読み込み中…