化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylformamide → 4-Benzyloxy-2-(trifluoromethyl)benzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | 4-(Benzyloxy)-1-bromo-2-(trifluoromethyl)benzene | HCID 22273864 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-Benzyloxy-2-(trifluoromethyl)benzaldehyde | HCID 22273885 | — |
反応手順
In analogy to the procedure described in example 8 c], 1-bromo-2-trifluoromethyl-4-(phenylmethoxy)-benzene was treated with n-BuLi and N,N-dimethylformamide in dry tetrahydrofuran to yield 4-benzyloxy-2-trifluoromethyl-benzaldehyde as colorless liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06969725B2 |
| 出典データセット | uspto-grants-2005_11 |
| ORD ID | ord-bc3bf74a827e44eba5c73ae78aa96eb5 |
| 出典メモ | uspto-grants-2005_11 |