化工社化工社 化学情報印刷レポート · 研究参考用
5-Bromo-2,4-dimethoxybenzaldehyde → 2,4-Dimethoxy-5-(5-methylthiophen-2-yl)-benzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Bromo-2,4-dimethoxybenzaldehyde | HCID 668346 | — |
| 反応物 | (5-Methylthiophen-2-yl)boronic acid | HCID 2734374 | — |
| 生成物 | 2,4-Dimethoxy-5-(5-methylthiophen-2-yl)-benzaldehyde | HCID 16115913 | 100% |
反応手順
Ex-40A: 2,4-Dimethoxy-5-(5-methyl-thiophen-2-yl)-benzaldehyde was prepared from 5-bromo-2,4-dimethoxybenzaldehyde and 5-methyl-thiophene-2-boronic acid in a similar manner as described in Ex-3A, 100% yield. 1H-NMR (CDCl3) δ 10.33 (s, 1H), 8.05 (s, 1H), 7.22 (d, J=4 Hz, 1H), 6.72 (d, J=4 Hz, 1H), 6.49 (s, 1H), 4.00 (s, 3H), 3.97 (s, 3H), 2.50 (s, 3H). HMRS (EI) calcd. for C14H14O3S: 262.0664; found: 262.0665.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07094801B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-dd0ec8ebfe9741fe8411348cbbc1cf68 |
| 出典メモ | uspto-grants-2006_08 |