Dimethyl Sulfoxide → 2,3-Dichloro-4-(3-hydroxy-2-methylpyrrolidin-1-yl)benzonitrile

反応式

[CH3:12][CH:13]1[NH:14][CH2:15][CH2:16][CH:17]1[OH:18].[CH3:19][S:20](=[O:21])[CH3:22].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([F:11])[c:9]1[Cl:10].[Li+:23].[Li+:24].[O-:25][C:26](=[O:27])[O-:28]>>[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([N:14]2[CH:13]([CH3:12])[CH:17]([OH:18])[CH2:16][CH2:15]2)[c:9]1[Cl:10]