Ethyl Acetate → HCID 178456966、化合物

HRID 1066135ノート

反応式

HRID 1066135 の反応式
[NH2:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[S:12]([NH2:15])(=[O:14])=[O:13].[CH:16]([N:19]=[C:20]=S)([CH3:18])[CH3:17].C(OCC)(=O)C>O>[CH:16]([NH:19][C:20]1[NH:1][C:2]2[CH:7]=[C:6]([C:8]([F:9])([F:11])[F:10])[CH:5]=[CH:4][C:3]=2[S:12](=[O:14])(=[O:13])[N:15]=1)([CH3:18])[CH3:17]

参加物

5

反応物 3

HCID 8857Ethyl AcetateHCID 75263Isopropyl IsothiocyanateHCID 13486675657-70-5

生成物 1

HCID 178456966HCID 178456966、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The title compound was prepared from 2-amino-4-trifluoromethylbenzenesulfonamide and isopropyl isothiocyanate by a method analogous to the one described in Example 4; m.p. 294-297° C. (ethyl acetate); 1H-NMR (DMSO-d6): δ 1.20 (d, 6H, CH(CH3)2), 3.95 (m, 1H, CH(CH3)2), 7.42 (br., 1H, NH), 7.56 (m, 2H, ArH), 7.99 (d, 1H, ArH), 10.55 (br.s, 1H, NH); MS: m/e 307 (M+, 33%); (C11H12N3F3O2S1.H2O) calc. C, 40.6; H, 4.3; N, 12.9; found C, 41.0; H, 4.1; N, 13.1.

出典と根拠

ORDレコード
ord-9c523088b61b43ddbbb04c3cf86fd6ef
出典データセット
uspto-grants-2001_06
特許番号
US06242443B1

反応ノート

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