Ammonia → Octyl 4'-hydroxy-4-biphenylcarboxylate

HRID 1066545ノート

反応式

HRID 1066545 の反応式
COC([O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)=O.N.ClCCl>C(O)C>[OH:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:19])=[CH:14][CH:13]=2)=[CH:10][CH:11]=1

参加物

5

反応物 3

HCID 222AmmoniaHCID 6344DichloromethaneHCID 18328376Octyl4'-methoxycarbonyloxy-4-biphenylcarboxylate

生成物 1

HCID 14692993Octyl 4'-hydroxy-4-biphenylcarboxylate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of compound 5 (5.25 g, 0.014 mol) and aqueous ammonia (35% w/v, 100 ml) in ethanol (200 ml) was stirred for 1 h at room temperature. TLC analysis (dichloromethane) revealed a complete reaction. The solvent was removed in vacuo and the shite solid was recrystallised from ethanol to give colourless crystals.

後処理

  1. customa complete reaction
  2. customThe solvent was removed in vacuo
  3. customthe shite solid was recrystallised from ethanol
  4. customto give colourless crystals

出典と根拠

ORDレコード
ord-4c0928ed998b44f0abc8a9f40a5bde1b
出典データセット
uspto-grants-2001_06
特許番号
US06242636B1

反応ノート

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