5-Ethyl-2-methylpyridine → (5-Ethylpyridin-2-yl)methyl acetate

反応式

[C:1]([O:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][N:7]=1)(=[O:3])[CH3:2].[CH2:13](C1C=CC(C)=NC=1)C>>[C:1]([O:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH3:13])=[CH:8][N:7]=1)(=[O:3])[CH3:2]

参加物

反応物 2

HCID 77285-Ethyl-2-methylpyridine

HCID 123253842-Pyridinemethanol, 5-methyl-, 2-acetate

生成物 1

HCID 14346253(5-Ethylpyridin-2-yl)methyl acetate収率 89%

実験手順

This synthesis was performed analogously to the synthesis reported for 2-acetoxymethyl-5-methyl pyridine. Starting from 5-ethyl-2-methyl pyridine (35.10 g, 290 mmol), pure 2-acetoxymethyl-5-ethyl pyridine (46.19 g, 258 mmol, 89%) was obtained as a slightly yellow oil.

出典と根拠

ORDレコード: ord-452899ae26074788ab4ecf84295d2d59
出典データセット: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06245115B1

反応ノート

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