Cetylpyridinium Chloride → HCID 178443017、化合物
反応式
[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N+:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1.[Cl-:23].[CH3:24][N:25]1[N:31]=[C:30]([OH:32])[C:28](=[O:29])[N:27]=[C:26]1[S:33][CH2:34][C:35]1[CH2:56][S:55][C@@H:38]2[C@H:39]([NH:42][C:43](/[C:45](/[C:49]3[N:53]=[C:52]([NH2:54])[S:51][CH:50]=3)=[N:46]\[O:47][CH3:48])=[O:44])[C:40](=[O:41])[N:37]2[C:36]=1[C:57]([OH:59])=[O:58]>O>[CH3:24][N:25]1[N:31]=[C:30]([OH:32])[C:28](=[O:29])[N:27]=[C:26]1[S:33][CH2:34][C:35]1[CH2:56][S:55][C@@H:38]2[C@H:39]([NH:42][C:43](/[C:45](/[C:49]3[N:53]=[C:52]([NH2:54])[S:51][CH:50]=3)=[N:46]\[O:47][CH3:48])=[O:44])[C:40](=[O:41])[N:37]2[C:36]=1[C:57]([OH:59])=[O:58].[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N+:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[Cl-:23]参加物
実験手順
About 210 mg (0.62 mole) of particulate cetyl pyridinium chloride was dissolved in 50 ml of distilled water. Additionally, about 378 mg (0.62 mole) of ceftriaxone was dissolved in 50 ml of a separate volume of distilled water. Next, the ceftriaxone solution was added to the cetyl pyridinium chloride solution and stirred by a magnetic stirrer at room temperature for 1 hour forming a ceftriaxone-cetyl pyridinium chloride solution. About 400 mg of carrageenan was added to the ceftriaxone-cetyl pyridinium chloride solution and the solution was stirred by magnetic stirrer at room temperature for 2 hours. A ceftriaxone-cetyl pyridinium chloride-carrageenan hydrogel complex was formed. The complex was then freeze-dried while in the swollen state, yielding about 0.86 g of the freeze dried complex.
出典と根拠
- ORDレコード
- ord-c1df30ed15824c2681bec1c02e62b7d1
- 出典データセット
- uspto-grants-2001_06
- 特許番号
- US06248360B1
反応ノート
読み込み中…