Ammonium dithiocarbamate → Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate

HRID 1067404

反応式

HRID 1067404 の反応式
[CH2:1]([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[C:16]2[CH2:15][CH2:14][CH2:13][C:12](=O)[C:11]=2[CH:10]=[CH:9][C:8]=1Br)[CH3:2].[C:20](=[S:23])([S-:22])[NH2:21].[NH4+]>C(O)C>[CH2:1]([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:16]=1[CH2:15][CH2:14][C:13]1[S:22][C:20]([SH:23])=[N:21][C:12]=12)[CH3:2]

参加物

4

反応物 2

HCID 11083854Ammonium dithiocarbamateHCID 21193671Ethyl [(2-bromo-5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxy]acetate

生成物 1

HCID 178472952Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate収率 76%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of ethyl[(2-bromo-5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxy]acetate (2.63 g, 8.04 mmol), ammonium dithiocarbamate (1.06 g, 9.60 mmol), and ethanol (30 mL) was refluxed for 14 hours. After cooling, the solid precipitate was recovered by filtration to provide 1.96 g of the title compound. Amorphous solid. Yield 76%.

後処理

  1. temperaturewas refluxed for 14 hours
  2. temperatureAfter cooling
  3. filtrationthe solid precipitate was recovered by filtration

出典と根拠

ORDレコード
ord-6f5f3deb684e4dc4b6e97db8d01c6841
出典データセット
uspto-grants-2001_06
特許番号
US06248766B1

関連ノート

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