Chlorotriethylsilane → n,n-Diethyl-2-chloro-6-(triethylsilyl)benzamide

HRID 1068283ノート

反応式

HRID 1068283 の反応式
[CH2:1]([N:3]([CH2:13][CH3:14])[C:4](=[O:12])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:2].Cl[Si:16]([CH2:21][CH3:22])([CH2:19][CH3:20])[CH2:17][CH3:18]>>[CH2:13]([N:3]([CH2:1][CH3:2])[C:4](=[O:12])[C:5]1[C:10]([Si:16]([CH2:21][CH3:22])([CH2:19][CH3:20])[CH2:17][CH3:18])=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:14]

参加物

3

反応物 2

HCID 13819ChlorotriethylsilaneHCID 825662-Chloro-N,N-diethylbenzamide

生成物 1

HCID 18630182n,n-Diethyl-2-chloro-6-(triethylsilyl)benzamide

実験手順

The title compound was prepared according to General Method A from the compound of Example e and 1.4 eq chlorotriethylsilane. Purification by HPLC with 1:19 ethyl acetate/hexanes gave 6.0 g of the desired product as a clear oil, a 92% yield.

後処理

  1. customThe title compound was prepared
  2. customPurification by HPLC with 1:19 ethyl acetate/hexanes

出典と根拠

ORDレコード
ord-7c7bba4a800747729ff5b7330a265047
出典データセット
uspto-grants-2001_06
特許番号
US06248894B1

反応ノート

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