Acetone → N-[4-amino-5-(5-iodo-2-isopropyl-4-methoxy-phenoxy)-pyrimidin-2-yl]-2-(2,6-dimethyl-morpholin-4-yl)-acetamide

反応式

[CH3:26][CH:27]1[O:28][CH:29]([CH3:33])[CH2:30][NH:31][CH2:32]1.[CH3:36][C:37](=[O:38])[CH3:39].[I-:35].[NH2:1][c:2]1[n:3][c:4]([NH:21][C:22]([CH2:23][Cl:24])=[O:25])[n:5][cH:6][c:7]1[O:8][c:9]1[c:10]([CH:18]([CH3:19])[CH3:20])[cH:11][c:12]([O:16][CH3:17])[c:13]([I:15])[cH:14]1.[Na+:34]>>[NH2:1][c:2]1[n:3][c:4]([NH:21][C:22]([CH2:23][N:31]2[CH2:30][CH:29]([CH3:33])[O:28][CH:27]([CH3:26])[CH2:32]2)=[O:25])[n:5][cH:6][c:7]1[O:8][c:9]1[c:10]([CH:18]([CH3:19])[CH3:20])[cH:11][c:12]([O:16][CH3:17])[c:13]([I:15])[cH:14]1