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trans-2-Phenylcyclopropyl isocyanate → N-{4-[4-amino-2-(ethoxymethyl)-6-methyl-1H-imidazo[4,5-c]pyridin-1-yl]butyl}-N'-[(1R*,2S*)-2-phenylcyclopropyl]urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | trans-2-Phenylcyclopropyl isocyanate | HCID 255285 | — |
| 反応物 | 1-(4-aminobutyl)-2-ethoxymethyl-6-methyl-1H-imidazo[4,5-c]pyridin-4-amine | HCID 12972960 | — |
| 生成物 | N-{4-[4-amino-2-(ethoxymethyl)-6-methyl-1H-imidazo[4,5-c]pyridin-1-yl]butyl}-N'-[(1R*,2S*)-2-phenylcyclopropyl]urea | HCID 20575811 | — |
反応手順
Using the method of Examples 36-45, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(4-aminobutyl)-2-ethoxymethyl-6-methyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 437.2666.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06903113B2 |
| 出典データセット | uspto-grants-2005_06 |
| ORD ID | ord-9177b65a252049ba979555db66bdaeaf |
| 出典メモ | uspto-grants-2005_06 |