Ethylamine → 29526-66-7

HRID 1071511ノート

反応式

HRID 1071511 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-])=O.[CH2:14]([NH2:16])[CH3:15]>C(Cl)Cl>[NH2:11][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:2]=1[CH3:1])[C:6]([NH:16][CH2:14][CH3:15])=[O:7]

参加物

4

反応物 2

HCID 6341EthylamineHCID 663234-Methyl-3-nitrobenzoyl chloride

生成物 1

HCID 1260797429526-66-7

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

反応条件

温度
0 °C

実験手順

4-methyl-3-nitro-benzoyl chloride (1.0 g, 5.0 mmol) was dissolved in DCM, and the solution was cooled to 0° C. Ethyl amine (2.0 M in THF, 5.0 mL, 10 mmol) was added dropwise to the acid chloride, and the reaction stirred at 0° C. for 5 min. The ice bath was removed and reaction continued to stir for 3. The solution was washed with brine, dried (Na2SO4), and concentrated in vacuo. The resulting aniline (0.75 g) was used without further purification.

後処理

  1. customThe ice bath was removed
  2. customreaction
  3. stirringto stir for 3
  4. washThe solution was washed with brine
  5. dry with materialdried (Na2SO4)
  6. concentrationconcentrated in vacuo
  7. customThe resulting aniline (0.75 g) was used without further purification

出典と根拠

ORDレコード
ord-2dff38dbaa724d6d8ccc0f12cda4885a
出典データセット
uspto-grants-2005_06
特許番号
US06906067B2

反応ノート

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