α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → 1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-methoxymethyl-2-pyridyloxy)ethyl]-piperazine

HRID 1071660ノート

反応式

HRID 1071660 の反応式
[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[CH3:16][O:17][CH2:18][C:19]1[N:24]=[C:23]([O:25][CH2:26][CH2:27][N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH:22]=[CH:21][CH:20]=1>>[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:31]1[CH2:32][CH2:33][N:28]([CH2:27][CH2:26][O:25][C:23]2[CH:22]=[CH:21][CH:20]=[C:19]([CH2:18][O:17][CH3:16])[N:24]=2)[CH2:29][CH2:30]1)#[N:2]

参加物

3

反応物 2

HCID 22393563α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 223936901-(2-(6-Methoxymethyl-2-pyridyloxy)ethyl]piperazine

生成物 1

HCID 223936471-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-methoxymethyl-2-pyridyloxy)ethyl]-piperazine

実験手順

The titile compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-(2-(6-methoxymethyl-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.

出典と根拠

ORDレコード
ord-ce1d8fe6879f46bcafa839ed7e57765d
出典データセット
uspto-grants-2005_06
特許番号
US06906072B1

反応ノート

読み込み中…