Cyclohexanecarbonyl chloride → Benzimidazole

HRID 1072535ノート

反応式

HRID 1072535 の反応式
NC1C=CC([C:8]2[NH:9][C:10]3[CH:16]=[CH:15][C:14](N)=[CH:13][C:11]=3[N:12]=2)=CC=1.C1(C(Cl)=O)CCCCC1>>[N:9]1[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[NH:12][CH:8]=1

参加物

3

反応物 2

HCID 75938Cyclohexanecarbonyl chlorideHCID 178507432HCID 178507432、化合物

生成物 1

HCID 5798Benzimidazole

実験手順

2-(N-Cyclohexylcarbonyl-4′-aminophenyl)-6-cyclohexylcarbonylamino)-benzimidazole was prepared by Method A from 2-(4-aminophenyl)-6-aminobenzimidazole (0.195 g, 0.87 mmole) and cyclohexylcarbonyl chloride (0.291 ml, 0.319 g, 2.175 mmole). The resulting solid (76.7 mg) was purified by preparative HPLC.

後処理

  1. customThe resulting solid (76.7 mg) was purified by preparative HPLC

出典と根拠

ORDレコード
ord-846edf29646848ffb9b26b83d99d7e9d
出典データセット
uspto-grants-2005_06
特許番号
US06911462B2

反応ノート

読み込み中…