4-Phenylbenzoyl chloride → HCID 22387999、化合物

反応式

[Cl-].[Al+3].[Cl-].[Cl-].[C:5]1([C:11]2[CH:19]=[CH:18][C:14]([C:15](Cl)=[O:16])=[CH:13][CH:12]=2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[CH3:20][O:21][C:22]([C:24]1[CH:33]=[CH:32][C:27]2[O:28][C:29]([CH3:31])=[CH:30][C:26]=2[CH:25]=1)=[O:23]>C(Cl)Cl>[CH3:20][O:21][C:22]([C:24]1[CH:33]=[CH:32][C:27]2[O:28][C:29]([CH3:31])=[C:30]([C:15](=[O:16])[C:14]3[CH:18]=[CH:19][C:11]([C:5]4[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=4)=[CH:12][CH:13]=3)[C:26]=2[CH:25]=1)=[O:23]

参加物

実験手順

Aluminum chloride (0.80 g) was stirred in methylene chloride (10 ml) at room temperature. Thereto was added 4-phenylbenzoyl chloride (0.67 g), and then a solution of 5-(methoxycarbonyl)-2-methylbenzo[b]furan (0.67 g) in methylene chloride (5 ml), and the mixture was stirred for 4 hr. Ice was added to the reaction mixture and the mixture was extracted with ethyl acetate. The extract was washed with a saturated aqueous solution of sodium hydrogencarbonate (twice) and saturated brine (once), dried over sodium sulfate and concentrated to give the objective compound (1.36 g).