Water → 3-Amino-2-(4-chlorophenyl)-4-quinolinecarboxylic acid
反応式
[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4](=O)[C:2]1=[O:3].Cl.[NH2:13][CH2:14][C:15]([C:17]1[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=1)=O.[OH2:24]>>[NH2:13][C:14]1[C:15]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[N:1][C:11]2[C:6]([C:4]=1[C:2]([OH:24])=[O:3])=[CH:7][CH:8]=[CH:9][CH:10]=2参加物
4
実験手順
A solution of 5.8 g of isatin in water was reacted with 12.0 g of 2-amino-1-(4-chlorophenyl)ethanone hydrochloride by the procedure described in example 33, giving 8.1 g of the desired compound as a yellow solid, mp 243°-244° C.
出典と根拠
- ORDレコード
- ord-6fbb4555491d463d9552b2af142c8680
- 出典データセット
- uspto-grants-1990_11
- 特許番号
- US04968702
反応ノート
読み込み中…