4-(Trifluoromethyl)benzoic acid → 4-(Trifluoromethyl)benzoyl bromide
反応式
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][CH:4]=1.P(Br)(Br)[Br:15]>>[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7]([Br:15])=[O:8])=[CH:5][CH:4]=1参加物
3
実験手順
In a 50 ml glass reactor, 30 g of 4-trifluoromethylbenzoic acid and 14.5 g of phosphorus tribromide were reacted at 155° C. for 3 hr. After that the reaction liquid was distilled under reduced pressure to obtain 23 g of 4-trifluoromethylbenzoyl bromide having a boiling point of 88°-89° C. at 18 mmHg. The yield in this reaction was 58%.
後処理
- customAfter that the reaction liquid
- distillationwas distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-37debe9c721a41708dc79f130d3dd352
- 出典データセット
- uspto-grants-1990_11
- 特許番号
- US04968852
反応ノート
読み込み中…