4-Nitrophenol → 4-(1-Trifluoromethylethoxy)phenol

反応式

CS([O:5][CH:6]([C:8]([F:11])([F:10])[F:9])[CH3:7])(=O)=O.[N+]([C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=1)([O-])=O>>[F:9][C:8]([F:11])([F:10])[CH:6]([O:5][C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=1)[CH3:7]

参加物

反応物 2

HCID 9804-Nitrophenol

HCID 156290151-Trifluoromethylethyl methanesulfonate

生成物 1

HCID 198165474-(1-Trifluoromethylethoxy)phenol

実験手順

Following the above procedures, 1-trifluoromethylethyl methanesulfonate is reacted with 4-nitrophenol to give 4-(1trifluoromethylethoxy)phenol, which is then reacted with ethyl N-(2-chloroethyl)carbamate to give ethyl N-{2-[4-(1-trifluoromethylethoxy)phenoxy]ethyl}carbamate (compound 29, Table A).

出典と根拠

ORDレコード: ord-b60c36021e9d4778a701aaacfececc6e
出典データセット: uspto-grants-1990_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04968829

反応ノート

読み込み中…