3-Decynoic acid → Dec-3-enoic acid
反応式
[C:1]([OH:12])(=[O:11])[CH2:2][C:3]#[C:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>CO.B#[Ni]>[C:1]([OH:12])(=[O:11])[CH2:2][CH:3]=[CH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]参加物
4
実験手順
To 4.5 g (27 mmol) of 3-decynoic acid from Example 30 dissolved in methanol in a Paar bottle is added 2 mg of nickel boride as catalyst. The bottle is flushed with hydrogen, sealed and pressurized with H2 at 2 pounds per square inch. The hydrogenation is allowed to proceed at room temperature for 2 hours. The methanol is stripped in vacuo and the residue is partitioned between ethyl acetate and in HCl. The ethyl acetate layer is separated, dried, (Na2SO4) and is stripped to afford an almost quantitative yield of 3-decenoic acid.
後処理
- customThe bottle is flushed with hydrogen
- customsealed
- customthe residue is partitioned between ethyl acetate and in HCl
- customThe ethyl acetate layer is separated
- customdried
出典と根拠
- ORDレコード
- ord-35cb007cd34a4d809d2f69580f544f96
- 出典データセット
- uspto-grants-1990_11
- 特許番号
- US04970234
反応ノート
読み込み中…