化工社化工社 化学情報印刷レポート · 研究参考用
o-Xylyl bromide → Ethyl (2-methylbenzylthio)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | o-Xylyl bromide | HCID 6992 | — |
| 反応物 | Ethyl Thioglycolate | HCID 12185 | — |
| 反応物 | Sodium ethoxide | HCID 2723922 | — |
| 反応物 | Ethyl (4-methylbenzylthio)acetate | HCID 4107274 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Ethyl (2-methylbenzylthio)acetate | HCID 13245059 | — |
反応手順
The procedure is as in Example 29 for the preparation of ethyl (4-methylbenzylthio)acetate, starting with 2-bromomethyltoluene (10 g), a 2M ethanolic solution of sodium ethylate (30 cc) and ethyl 2-mercaptoacetate (6.5 g), in ethanol (100 cc). Ethyl (2-methylbenzylthio)acetate (8.9 g) is thereby obtained, and is used in the crude state in the subsequent syntheses.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04971979 |
| 出典データセット | uspto-grants-1990_11 |
| ORD ID | ord-8be7b2a72c794538966f31b125c630d7 |
| 出典メモ | uspto-grants-1990_11 |