Hydrochloric Acid → 2-[(4-Nitrophenyl)thio]-1-phenyl-1H-imidazole hydrochloride

反応式

[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[N:12]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:13]=[CH:14][N:15]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[ClH:22]>>[ClH:22].[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[N:12]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:13]=[CH:14][N:15]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

参加物

反応物 2

HCID 313Hydrochloric Acid

HCID 150774972-[(4-Nitrophenyl)thio]-1-phenyl-1H-imidazole

生成物 1

HCID 221559862-[(4-Nitrophenyl)thio]-1-phenyl-1H-imidazole hydrochloride

実験手順

The product from Example 24 was converted to the hydrochloride salt by treatment with ethanolic hydrogen chloride. After recrystallization from methanol/isopropanol/ether the product was obtained off-white prisms, mp 215°-218° C.

後処理

customAfter recrystallization from methanol/isopropanol/ether the product
customwas obtained off-white prisms, mp 215°-218° C.

出典と根拠

ORDレコード: ord-7d9e1ea2855c401a9e1f18b748e65495
出典データセット: uspto-grants-1990_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04973599

反応ノート

読み込み中…

参加物