化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl 4-Hydroxybenzoate → Benzoic acid, 4-(phenylmethoxy)-, phenylmethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl 4-Hydroxybenzoate | HCID 7180 | — |
| 反応物 | O-Xylene | HCID 7237 | — |
| 反応物 | Benzyl Chloride | HCID 7503 | — |
| 反応物 | Sodium 4-hydroxybenzoate | HCID 16219477 | — |
| 触媒 | Tetrabutylammonium Chloride | HCID 70681 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | Benzoic acid, 4-(phenylmethoxy)-, phenylmethyl ester | HCID 91863 | 73% |
反応手順
Sodium p-hydroxybenzoate (64 g) and 51 g of benzyl chloride were added to 300 g of xylene, and 1.3 g of tetrabutyl ammonium chloride as a phase transfer catalyst and 2 g of methyl ethyl ketone were added. The mixture was refluxed for 8 hours Benzyl p-hydroxybenzoate was obtained in a yield of 73%, and the ratio of benzyl p-benzyloxybenzoate formed was 13%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04973737 |
| 出典データセット | uspto-grants-1990_11 |
| ORD ID | ord-134e8fd2534d44edb64b6d218002ce3e |
| 出典メモ | uspto-grants-1990_11 |