Morpholine → HCID 13175260、化合物

HRID 1074388ノート

反応式

HRID 1074388 の反応式
Cl[C:2]1[CH:14]=[CH:13][C:5]2=[N:6][C:7]3[CH2:12][CH2:11][CH2:10][CH2:9][C:8]=3[N:4]2[N:3]=1.[NH:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1>>[N:15]1([C:2]2[CH:14]=[CH:13][C:5]3=[N:6][C:7]4[CH2:12][CH2:11][CH2:10][CH2:9][C:8]=4[N:4]3[N:3]=2)[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

参加物

3

反応物 2

HCID 8083MorpholineHCID 11148455HCID 11148455、化合物

生成物 1

HCID 13175260HCID 13175260、化合物

実験手順

A mixture was prepared by adding 5.0 g of 2-chloro-6,7,8,9-tetrahydropyridazino[1,6-a]benzimidazole to 30 ml of morpholine and this was stirred and heated at reflux for 24 hours. It was then poured into 200 ml of ice water. A tan solid formed and this was separated by filtration to give 2-(4-morpholinyl)-6,7,8,9-tetrahydropyridazino[1,6-a]benzimidazole melting at 187.5°-188.5° C.

後処理

  1. customA mixture was prepared
  2. temperatureheated
  3. temperatureat reflux for 24 hours
  4. customA tan solid formed
  5. customthis was separated by filtration

出典と根拠

ORDレコード
ord-dc5e57af1b4a498394618e559a8fb055
出典データセット
uspto-grants-1983_07
特許番号
US04391806

反応ノート

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