Epichlorohydrin → HCID 20496759、化合物
反応式
[OH:1][C:2]1[CH:17]=[CH:16][C:5]2[CH2:6][CH:7]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH2:8][O:9][C:4]=2[CH:3]=1.N1CCCCC1.Cl[CH2:25][CH:26]1[O:28][CH2:27]1>>[O:28]1[CH:26]([CH2:25][O:1][C:2]2[CH:17]=[CH:16][C:5]3[CH2:6][CH:7]([C:10]4[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=4)[CH2:8][O:9][C:4]=3[CH:3]=2)[CH2:27]1参加物
4
実験手順
17 g 7-hydroxy-3-phenyl-3,4-dihydro-2H-1-benzopyrane, 0.1 cm3 piperidine and 100 cm3 1-chloro-2,3-epoxypropane were stirred for 6 hours at a temperature of 90° C. The solution was evaporated under reduced pressure, the residue was dissolved in 150 cm3 benzene and the obtained solution was extracted twice with 25--25 cm3 saturated sodium carbonate solution. The benzene phase was separated from the precipitated resin, clarificated with charcoal, filtered and evaporated. Crystallizing the residue from methanol, 15 g pure crystalline 1,2-epoxy-3-(3-phenyl-3,4-dihydro-2H-1-benzopyrane-7-yloxy)-propane was obtained (m.p. 117°-119° C.).
後処理
- custom