4,6-Dimethylpyrimidin-2-ol → 5-Chloro-4,6-dimethyl-pyrimidin-2-ol

HRID 1075162

反応式

HRID 1075162 の反応式
[Cl:1]Cl.[CH3:3][C:4]1[CH:9]=[C:8]([CH3:10])[NH:7][C:6](=[O:11])[N:5]=1>C(OC(=O)C)(=O)C>[CH3:3][C:4]1[C:9]([Cl:1])=[C:8]([CH3:10])[NH:7][C:6](=[O:11])[N:5]=1

参加物

4

反応物 2

HCID 95084,6-Dimethylpyrimidin-2-olHCID 24526Chlorine

生成物 1

HCID 204942805-Chloro-4,6-dimethyl-pyrimidin-2-ol

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒2 回

実験手順

A solution of chlorine (0.01 mol) in acetic anhydride (100 ml) was added to a solution of 4,6-dimethylpyrimid-2-one (0.008 mol) in acetic anhydride (100 ml) and the solution left at room temperature for 1 hr before the solid precipitate was collected and recrystallised from water; m.p. 235° C. (decomp.)

後処理

  1. customwas collected
  2. customrecrystallised from water

出典と根拠

ORDレコード
ord-c1dc9053935c423e85228be8e8522698
出典データセット
uspto-grants-1983_07
特許番号
US04395406

関連ノート

読み込み中…