化工社化工社 化学情報印刷レポート · 研究参考用
Water → Acifluorfen-methyl
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Chlorine | HCID 24526 | — |
| 反応物 | Methyl 2-nitro-5-[4-(trifluoromethyl)phenoxy]benzoate | HCID 13209694 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Acifluorfen-methyl | HCID 91642 | — |
反応手順
Methyl 5-(4-trifluoromethylphenoxy)-2-nitrobenzoate is stirred with a catalytic amount of ferric chloride. The reaction mixture was heated to 70° C. under a continuous stream of chlorine gas. After 2.5 hours, the mixture was taken up in ether, shaken with water and the organic phase was dried over MgSO4. The ether was evaporated to afford methyl 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate. NMR (CDCl3)δ8.2-7 (m,6) 4.0 (2,3). TLC (40% ether/hexane) Rf ≈.4.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04395570 |
| 出典データセット | uspto-grants-1983_07 |
| ORD ID | ord-c85e0659d8554c0b9334c310b60f0b5a |
| 出典メモ | uspto-grants-1983_07 |