1-Methyl-4-piperidone → 5-Methoxy-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)pyrrolo[3,2-b]pyridine
反応式
[CH3:1][O:2][C:3]1[N:8]=[C:7]2[CH:9]=[CH:10][NH:11][C:6]2=[CH:5][CH:4]=1.[CH3:12][N:13]1[CH2:18][CH2:17][C:16](=O)[CH2:15][CH2:14]1>>[CH3:1][O:2][C:3]1[N:8]=[C:7]2[C:9]([C:16]3[CH2:17][CH2:18][N:13]([CH3:12])[CH2:14][CH:15]=3)=[CH:10][NH:11][C:6]2=[CH:5][CH:4]=1参加物
3
実験手順
Beginning with 0.80 gm (5.4 mMol) of 5-methoxypyrrolo-[3,2-b]pyridine and 1.2 mL (10.1 mMol) 1-methyl-4-piperidone, 1.1 gm (84%) of the title compound were recovered as a yellow solid essentially by the procedure described in Example 5. An analytical sample was recrystallized from methanol.
出典と根拠
- ORDレコード
- ord-b4ed7dcdb7724f2985fc341b9c4689b3
- 出典データセット
- uspto-grants-1999_05
- 特許番号
- US05905084
反応ノート
読み込み中…