Potassium Carbonate → HCID 15858811、化合物
反応式
[CH2:1]([O:8][C:9]([NH:11][C@H:12]1[C@@H:15]([O:16][CH2:17][CH2:18]Br)[NH:14][C:13]1=[O:20])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([O-])([O-])=O.[K+].[K+]>CS(C)=O.C(OCC)(=O)C>[CH2:1]([O:8][C:9]([NH:11][C@@H:12]1[C:13](=[O:20])[N:14]2[C@@H:15]1[O:16][CH2:17][CH2:18]2)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
5
実験手順
A mixture of (3S,4R)-3-benzyloxycarbonylamino-4-bromoethoxy-azetidin-2-one (2.04 g, 5.945 mmole) and powder K2CO3 (903 mg, 6.54 mmole) in DMSO (20 ml) was stirred at room temperature overnight and then diluted with ethyl acetate, washed with cold water, brine, and dried over sodium sulfate. After removal of the solvent, 1.43 g of the title compound was obtained.
後処理
- washwashed with cold water, brine
- dry with materialdried over sodium sulfate
- customAfter removal of the solvent
出典と根拠
- ORDレコード
- ord-595b44bc05b14002a0858e41bc854793
- 出典データセット
- uspto-grants-1999_05
- 特許番号
- US05905076
反応ノート
読み込み中…