Diethyl aluminum cyanide → 2-(6'-Carbethoxyhexyl)-3-cyano-4-acetoxy-2-cyclopenten-1-one

HRID 1076018ノート

反応式

HRID 1076018 の反応式
[C:1]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]1[C:13](=[O:23])[CH2:14][CH:15]([O:19][C:20](=[O:22])[CH3:21])[C:16]=1OC)([O:3][CH2:4][CH3:5])=[O:2].[C-:24]#[N:25].C([Al+]CC)C>>[C:1]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]1[C:13](=[O:23])[CH2:14][CH:15]([O:19][C:20](=[O:22])[CH3:21])[C:16]=1[C:24]#[N:25])([O:3][CH2:4][CH3:5])=[O:2]

参加物

3

反応物 2

HCID 16686413Diethyl aluminum cyanideHCID 215414842-(6'-Carbethoxyhexyl)-3-methoxy-4-acetoxy-2-cyclopenten-1-one

生成物 1

HCID 215415072-(6'-Carbethoxyhexyl)-3-cyano-4-acetoxy-2-cyclopenten-1-one

実験手順

According to the procedure similar to that of Step 3 (a) of Example 1, 0.52 g of 2-(6'-carbethoxyhexyl)-3-methoxy-4-acetoxy-2-cyclopenten-1-one prepared in Step 2 was caused to react with diethylaluminum cyanide. Further, the product was purified using chromatography on silica gel to provide 0.25 g of 2-(6'-carbethoxyhexyl)-3-cyano-4-acetoxy-2-cyclopenten-1-one as an oily material.

後処理

  1. customFurther, the product was purified

出典と根拠

ORDレコード
ord-767804be100e4eb185b3ba75107a47d1
出典データセット
uspto-grants-1976_05
特許番号
US03954811

反応ノート

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