Bromine → 4-Bromo-5,6,7,8-tetrahydronaphthalen-1-ol

HRID 1076872ノート

反応式

HRID 1076872 の反応式
[C:1]1([OH:11])[C:10]2[CH2:9][CH2:8][CH2:7][CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[Br:12]Br>C(Cl)(Cl)(Cl)Cl>[Br:12][C:4]1[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[C:1]([OH:11])=[CH:2][CH:3]=1

参加物

4

反応物 2

HCID 24408BromineHCID 682585,6,7,8-Tetrahydro-1-naphthol

生成物 1

HCID 222364764-Bromo-5,6,7,8-tetrahydronaphthalen-1-ol収率 22.9%

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒2 回

実験手順

To a solution of 37 grams (0.25 mole) of 5,6,7,8-tetrahydronaphthol in 150 ml of carbon tetrachloride was added dropwise with stirring a solution of 44 grams (0.25 mole) of bromine in 50 ml of carbon tetrachloride. When the addition was complete the mixture was stirred for 30 minutes at room temperature and then evaporated in vacuo to a residue which after two recrystallizations from hexane provided 13 grams (22.9 percent) of product, m.p. 83°-85°C.

後処理

  1. additionWhen the addition
  2. customevaporated in vacuo to a residue which
  3. customafter two recrystallizations from hexane

出典と根拠

ORDレコード
ord-09abc6cc51ff4f11b20e62d4f0683c3b
出典データセット
uspto-grants-1976_05
特許番号
US03958006

反応ノート

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