Quinoline hydrochloride → Quinoline, 1,2,3,4-tetrahydro-, hydrochloride

反応式

[ClH:1].[N:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][CH:3]=1.Cl.N1C=CC=CC=1>>[ClH:1].[NH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH2:3]1

参加物

反応物 2

HCID 68264Quinoline hydrochloride

HCID 10176127Pyridinium chloride

生成物 1

HCID 520310Quinoline, 1,2,3,4-tetrahydro-, hydrochloride収率 100%

実験手順

By operating under the same conditions, but substituting 132 mg of 2,6-lutidine hydrochloride, 165 mg of quinoline hydrochloride and, respectively, 169 mg of 1,2,3,4-tetrahydroquinoline hydrochloride for pyridine hydrochloride, there is obtained 600 mg (25%) 560 mg (24%) and, respectively, 780 mg (33%) of pure product.

出典と根拠

ORDレコード: ord-342822bb576e42bd85964169ae44d23b
出典データセット: uspto-grants-1976_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03959266

反応ノート

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