Phenylglyoxylic acid hydrazide-2-acetylhydrazone → Metamitron
反応式
[C:1]([NH:4][N:5]=[C:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([NH:9][NH2:10])=[O:8])(=O)[CH3:2]>C(O)C>[NH2:10][N:9]1[C:7](=[O:8])[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[N:5][N:4]=[C:1]1[CH3:2]参加物
3
実験手順
175 g (0.8 mol) of phenylglyoxylic acid hydrazide-2-acetylhydrazone were dissolved in 2 liters of ethanol and the solution was heated to boil under reflux for 12 hours. After cooling, the product which had precipitated was filtered off. The mother liquor was partially freed from the solvent; on cooling, a further precipitate was obtained, which was also filtered off and well washed with water. The combined precipitates were dried. 123 g (76% of theory) of 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5-(4H)-one of melting point 160°-163°C. were obtained.
後処理
- temperaturethe solution was heated
- temperatureunder reflux for 12 hours
- temperatureAfter cooling
- customthe product which had precipitated
- filtrationwas filtered off
- temperatureon cooling
- customa further precipitate was obtained
- filtrationwhich was also filtered off
- washwell washed with water
- customThe combined precipitates
- customwere dried
出典と根拠
- ORDレコード
- ord-72eb00a67aea4d1995ab2d1f8e820036
- 出典データセット
- uspto-grants-1976_05
- 特許番号
- US03959372
反応ノート
読み込み中…