13beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one → Einecs 227-699-7

HRID 1077154

反応式

HRID 1077154 の反応式
[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C:7]1=[CH:6][CH2:5][C:4]2=[O:22])[CH3:2].[H][H]>O1CCOCC1.[Ni]>[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C@@H:7]1[CH2:6][CH2:5][C:4]2=[O:22])[CH3:2]

参加物

5

反応物 2

HCID 1097930013beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-oneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 111113Einecs 227-699-7収率 59.6%

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 312751,4-Dioxane溶媒

実験手順

Dissolve 13β-ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one (2 g) in dioxan (50 cc) containing Raney nickel (ca. 0.5 g) of moderate activity and shake with hydrogen until 160 cc., the amount corresponding to one molecular proportion has been absorbed. Recrystallize the isolated product from methanol to obtain the title product (1.2 g), m.p. 110°-125°; ultraviolet absorption peak at 280 mμ (ε13,200).

後処理

  1. custom, the amount corresponding to one molecular proportion has been absorbed
  2. customRecrystallize the isolated product from methanol

出典と根拠

ORDレコード
ord-ff9bc7ab3fa4433da1e738ad694f2d4a
出典データセット
uspto-grants-1976_05
特許番号
US03959322

関連ノート

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