trans-2,4,5-Trimethoxycinnamic acid → 147700-53-6

HRID 1077454ノート

反応式

HRID 1077454 の反応式
[NH2:1][C:2]1[C:3](=[O:16])[N:4]([CH2:13][CH2:14][CH3:15])[C:5](=[O:12])[N:6]([CH2:9][CH2:10][CH3:11])[C:7]=1[NH2:8].[CH3:17][O:18][C:19]1[CH:29]=[C:28]([O:30][CH3:31])[C:27]([O:32][CH3:33])=[CH:26][C:20]=1[CH:21]=[CH:22][C:23](O)=O>>[CH2:13]([N:4]1[C:3](=[O:16])[C:2]2[NH:1][C:23](/[CH:22]=[CH:21]/[C:20]3[CH:26]=[C:27]([O:32][CH3:33])[C:28]([O:30][CH3:31])=[CH:29][C:19]=3[O:18][CH3:17])=[N:8][C:7]=2[N:6]([CH2:9][CH2:10][CH3:11])[C:5]1=[O:12])[CH2:14][CH3:15]

参加物

3

反応物 2

HCID 91131trans-2,4,5-Trimethoxycinnamic acidHCID 50986055,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione

生成物 1

HCID 6448759147700-53-6収率 23%

実験手順

Substantially the same procedure as in Reference Example 1 was repeated using 2.00 g (8.85 mmol) of 5,6-diamino-1,3-dipropyluracil and 2.32 g (9.73 mmol) of 2,4,5-trimethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from 2-propanol/water to give 870 mg (yield 23%) of Compound 23 as a pale yellow powder.

後処理

  1. customThen, the resultant crude crystals were recrystallized from 2-propanol/water

出典と根拠

ORDレコード
ord-84fa942f9f0846e1af9e60da5f016fc9
出典データセット
uspto-grants-1996_08
特許番号
US05543415

反応ノート

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