化工社化工社 化学情報印刷レポート · 研究参考用
5,6-Diamino-1,3-diethyluracil → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethylphenyl)ethenyl)-, (E)-, hydrate (2:1)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 反応物 | 3-(2,5-Dimethylphenyl)prop-2-enoic acid | HCID 53401582 | — |
| 生成物 | 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethylphenyl)ethenyl)-, (E)-, hydrate (2:1) | HCID 6448872 | 50.1% |
反応手順
Substantially the same procedure as in Reference Example 70 was repeated using 3.00 g (15.1 mmol) of 5,6-diamino-1,3-diethyluracil and 3.20 g (18.2 mmol) of 2,5-dimethylcinnamic acid. Then, the resultant crude crystals were recrystallized from ethanol/toluene to give 2.56 g (yield 50%) of Compound 109 as white needles.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05543415 |
| 出典データセット | uspto-grants-1996_08 |
| ORD ID | ord-7d7f1239c5c64f02b2bd55edfc8d7fc6 |
| 出典メモ | uspto-grants-1996_08 |