5,6-Diamino-1,3-dimethyluracil → 155271-50-4

HRID 1077498ノート

反応式

HRID 1077498 の反応式
[NH2:1][C:2]1[C:3](=[O:12])[N:4]([CH3:11])[C:5](=[O:10])[N:6]([CH3:9])[C:7]=1[NH2:8].[Br:13][C:14]1[CH:15]=[C:16]([CH:22]=[CH:23][C:24]=1[O:25][CH3:26])[CH:17]=[CH:18][C:19](O)=O>>[Br:13][C:14]1[CH:15]=[C:16]([CH:22]=[CH:23][C:24]=1[O:25][CH3:26])/[CH:17]=[CH:18]/[C:19]1[NH:1][C:2]2[C:3](=[O:12])[N:4]([CH3:11])[C:5](=[O:10])[N:6]([CH3:9])[C:7]=2[N:8]=1

参加物

3

反応物 2

HCID 795015,6-Diamino-1,3-dimethyluracilHCID 7197543-(3-Bromo-4-methoxyphenyl)-2-propenoic acid

生成物 1

HCID 6448896155271-50-4収率 43.3%

実験手順

Substantially the same procedure as in Reference Example 70 was repeated using 2.00 g (11.8 mmol) of 5,6-diamino-1,3-dimethyluracil and 3.32 g (12.9 mmol) of 3-bromo-4-methoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dimethylformamide to give 2.00 g (yield 43%) of Compound 115 as a pale yellow powder.

後処理

  1. customThen, the resultant crude crystals were recrystallized from dimethylformamide

出典と根拠

ORDレコード
ord-b4f529cca1d145d68fd53b64da571593
出典データセット
uspto-grants-1996_08
特許番号
US05543415

反応ノート

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