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2,5-Dichloronitrobenzene → 4-Chloro-1-fluoro-2-nitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,5-Dichloronitrobenzene | HCID 6977 | — |
| 反応物 | Stearyltrimethylammonium chloride | HCID 8155 | — |
| 反応物 | Potassium Fluoride | HCID 522689 | — |
| 生成物 | 2,5-Dichloronitrobenzene | HCID 6977 | 29.7% |
| 生成物 | 4-Chloro-1-fluoro-2-nitrobenzene | HCID 67660 | 72.3% |
反応手順
2020 g (10.5 mol) of 2,5-dichloronitrobenzene, 70 g (0.2 mol) of octadecyltrimethylammonium chloride and 580 g (10.0 mol) of potassium fluoride were reacted analogously to Example 1. 936 g (72.3%, relative to 2,5-dichloronitrobenzene converted) of 2-fluoro-5-chloronitrobenzene and 600 g (29.7%, relative to 2,5-dichloronitrobenzene employed) of unreacted 2,5-dichloronitrobenzene were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05545768 |
| 出典データセット | uspto-grants-1996_08 |
| ORD ID | ord-241e020c2e9147949a0199531b862515 |
| 出典メモ | uspto-grants-1996_08 |