4'-Hydroxyacetophenone → 2-Bromo-1-(4-hydroxyphenyl)ethanone
反応式
[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[CH:8][CH:9]=1)=[O:3].[Br:11]Br>O1CCOCC1>[Br:11][CH2:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)=[O:3]参加物
4
実験手順
To a solution of 4-hydroxyacetophenone (2.5 g, 18.3 mmol) (Aldrich) in dioxane (10 mL) was added dropwise a solution of bromine (3.22 g, 20.1 mmol) in dioxane (20 mL). After stirring for 10 minutes, the mixture was concentrated in vacuo and the residue was recrystalized from methanol to provide 2-bromo-1-(4-hydroxyphenyl)ethanone (1.73 g, 44% yield).
後処理
- concentrationthe mixture was concentrated in vacuo
- customthe residue was recrystalized from methanol
出典と根拠
- ORDレコード
- ord-1467451901b34110b095a0f9bc4d4385
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07094896B2
反応ノート
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