Acetone → N-[(2-hydroxy)ethyl]-2,4-dimethylthiazolium bromide
反応式
[CH3:1][C:2]1[S:3][CH:4]=[C:5]([CH3:7])[N:6]=1.[O:8]1CCO[CH2:10][CH2:9]1.[Br:14]CCO.CC(C)=O>CCOCC>[Br-:14].[OH:8][CH2:9][CH2:10][N+:6]1[C:5]([CH3:7])=[CH:4][S:3][C:2]=1[CH3:1]参加物
6
実験手順
To the mixture of 2.4-dimethylthiazole (26.0 g) and dioxane (30 ml) was added 2-bromoethanol (40 g), and the resulting mixture was heated under reflux for 5 hours. To the mixture left standing at room temperature for about 0.5 hour was added acetone (150 ml) with stirring to give pale yellowish white solids. To the mixture was further added ether (150 ml), and the resulting powdery crystals were collected by filtration, washed with acetone and dried under reduced pressure.
後処理
- temperaturethe resulting mixture was heated
- temperatureunder reflux for 5 hours
- waitTo the mixture left
- customto give pale yellowish white solids
- filtrationthe resulting powdery crystals were collected by filtration
- washwashed with acetone
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-c4aaf398ecd4426f9a9669351438d1d8
- 出典データセット
- uspto-grants-1996_12
- 特許番号
- US05580904
反応ノート
読み込み中…