Acetone → HCID 23367237、化合物
反応式
[CH3:1][C:2]1[S:3][CH2:4][CH2:5][N:6]=1.[Br:7][CH2:8][CH2:9][OH:10].CC(C)=O.CCOCC>O1CCOCC1>[Br-:7].[OH:10][CH2:9][CH2:8][N+:6]1[CH:5]=[CH:4][S:3][C:2]=1[CH3:1]参加物
6
実験手順
To a solution of 2-methylthiazoline (10.1 g) in dioxane (20 ml) was added 2-bromoethanol (13.8 g), and the mixture was heated under reflux for about 6 hours. After cooling the reaction, acetone (30 ml) and ether (130 ml) were added with stirring, and the resulting mixture was left standing. After the pale brown supernatant was discarded, ether (150 ml) was further added to the amorphous precipitate thus obtained. The mixture was stirred and left standing. Supernatant obtained was discarded, and the viscous precipitates obtained was left standing at an ambient temperature under reduced pressure to give the title compound as the yellow amorphous residue.
後処理
- temperaturethe mixture was heated
- temperatureunder reflux for about 6 hours
- temperatureAfter cooling
- additionwere added
- waitthe resulting mixture was left
- customthus obtained
- stirringThe mixture was stirred
- waitleft
- customSupernatant obtained
- customthe viscous precipitates
- customobtained
- waitwas left
- customstanding at an ambient temperature under reduced pressure
出典と根拠
- ORDレコード
- ord-d8ac449be7624aadaab34d52356f45f4
- 出典データセット
- uspto-grants-1996_12
- 特許番号
- US05580904
反応ノート
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