Phenol → (1,1'-Biphenyl)-2-ol

HRID 1081129

反応式

HRID 1081129 の反応式
C1CCCCC=1.C1(O)C=CC=CC=1.C1(OC2C=CC=CC=2)CCCCC1.[CH:27]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=2[OH:39])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1>>[C:27]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=2[OH:39])[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1

参加物

5

反応物 4

HCID 996Phenol2 回HCID 8079Cyclohexene2 回HCID 8396o-CyclohexylphenolHCID 137492Benzene, (cyclohexyloxy)-2 回

生成物 1

HCID 7017(1,1'-Biphenyl)-2-ol

実験手順

The alkylation of Example 1A is repeated except the reaction is run at 140° C. The product contains 3.2 percent cyclohexene, 23.3 percent phenol, 13.7 cyclohexylphenyl ether, 57.7 percent ortho cyclohexyl phenol, and about 0.7 percent di-adduct. This product is then distilled in a POPE™ 2-inch wiped film still at 170° C., 1.7 psig (0.11 atm.) and 500 rpm (revolutions per minute). The heavies stream (distillation product which is not volatilized off) has about 0.7 percent cyclohexene, 44.3 percent phenol, 15.5 percent cyclohexylphenyl ether, 38 percent ortho cyclohexylphenol and 0.2 percent di-adduct. The heavies stream is reacted under the same conditions as Example 1A, except the reaction temperature is about 235° C. resulting in a product having about 0.05 percent cyclohexene, about 42.7 percent phenol, about 0.05 percent cyclohexylphenyl ether, about 53 percent orthocyclohexyphenol and about 0.4 percent di-adduct. This product from the heavies stream is then reacted under the same conditions as described by Example 1B. Example 1B resulted in essentially the same conversion and selectivity as described in Example 1B.

後処理

  1. customis run at 140° C
  2. distillationThis product is then distilled in a POPE™ 2-inch
  3. customstill at 170° C.
  4. distillationThe heavies stream (distillation product which
  5. customThe heavies stream is reacted under the same conditions as Example 1A, except the reaction temperature
  6. customis about 235° C.
  7. customresulting in a product
  8. customThis product from the heavies stream is then reacted under the same conditions
  9. customExample 1B resulted in essentially the same conversion and selectivity

出典と根拠

ORDレコード
ord-b2ba93d6c5ab4b37a94ef007779cad02
出典データセット
uspto-grants-1996_12
特許番号
US05583268

関連ノート

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