Benzene → 3-Benzoyl-2-thiophenecarboxylic acid

反応式

[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:8][C:9](=[O:10])[C:2]1=2)=[O:7].[Cl-].[Al+3].[Cl-].[Cl-].[CH:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:6]([C:3]1[CH:4]=[CH:5][S:1][C:2]=1[C:9]([OH:8])=[O:10])(=[O:7])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

参加物

反応物 3

HCID 241Benzene

HCID 222951thieno[2,3-c]furan-4,6-dione

HCID 6451240Aluminum(III) Chloride

生成物 1

HCID 3156073-Benzoyl-2-thiophenecarboxylic acid

実験手順

Employing 2,3-thiophene dicarboxylic anhydride and benzene, substantially the same reaction and work-up as in Reference Example 8 Step 1 in the presence of aluminum chloride were conducted to give 3-benzoyl-2-thiophenecarboxylic acid as colorless crystals.

出典と根拠

ORDレコード: ord-d9e59ea09be14f3f937361ad1a95346f
出典データセット: uspto-grants-1996_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05585385

反応ノート

読み込み中…