化工社化工社 化学情報印刷レポート · 研究参考用
Oxalyl chloride → 2,3,4,5-Tetrafluoro-6-methylbenzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 2,3,4,5-Tetrafluoro-6-methylbenzoic acid | HCID 12943997 | — |
| 触媒 | Dimethylformamide | HCID 6228 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2,3,4,5-Tetrafluoro-6-methylbenzoyl chloride | HCID 14651256 | 98.6% |
反応手順
A solution of 8.2 g (39.4 mmol) of 2,3,4,5-tetrafluoro-6-methylbenzoic acid, 6.0 g (47.2 mmol) of oxalyl chloride, and 100 mL of dichloromethane was treated with three drops of DMF. The solution was stirred for 3 hours, then concentrated to give 8.8 g of the title compound as a yellow liquid. The product was used as is in the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05585491 |
| 出典データセット | uspto-grants-1996_12 |
| ORD ID | ord-5d05344005574118b5d716446c84e88d |
| 出典メモ | uspto-grants-1996_12 |