反応式
[CH3:1][S:2]([NH:5][CH2:6][CH2:7][S:8][C:9]1[N:14]2[CH:15]=[CH:16][N:17]=[C:13]2[CH:12]=[CH:11][CH:10]=1)(=[O:4])=[O:3].[ClH:18].CO>CO>[CH3:1][S:2]([NH:5][CH2:6][CH2:7][S:8][C:9]1[N:14]2[CH:15]=[CH:16][N:17]=[C:13]2[CH:12]=[CH:11][CH:10]=1)(=[O:4])=[O:3].[ClH:18]参加物
4
実験手順
A suspension of 5-[2-(methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine (543 g, 2 mmoles) in methanol (20 ml) was treated with hydrogen chloride-methanol. After the solvent was distilled off, the residue was crystallized from chloroform ether. Then, the crystals thus obtained were washed with ether and dried to obtain 550 mg of the desired product (89.3%, colorless crystals).
後処理
- distillationAfter the solvent was distilled off
- customthe residue was crystallized from chloroform ether
- customThen, the crystals thus obtained
- washwere washed with ether
- customdried
出典と根拠
- ORDレコード
- ord-df264766d11c40e7b7945e674cf3610d
- 出典データセット
- uspto-grants-1996_12
- 特許番号
- US05587383
関連ノート
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