Cyclohexane → 3-Trifluoromethyl-2-(2-aminophenylthio)benzonitrile
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[F:9][C:10]([F:21])([F:20])[C:11]1[C:12](F)=[C:13]([CH:16]=[CH:17][CH:18]=1)[C:14]#[N:15].C1CCCCC1>CN(C=O)C>[F:9][C:10]([F:20])([F:21])[C:11]1[C:12]([S:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH2:1])=[C:13]([CH:16]=[CH:17][CH:18]=1)[C:14]#[N:15]参加物
5
実験手順
Using a procedure analagous to that of Example 3(a), 2-aminothiophenol (6.26 g, 50 mmol) was combined with 3-trifluoromethyl-2-fluorobenzonitrile (1 eq) in DMF solvent (50 ml) to give the title compound as a white solid from cyclohexane (10.41 g).
出典と根拠
- ORDレコード
- ord-ae940f8d208346e8bf6e1fa1a5e2df22
- 出典データセット
- uspto-grants-1996_12
- 特許番号
- US05589474
反応ノート
読み込み中…