Potassium Carbonate → HCID 178488708、化合物

反応式

Cl.[C:2]([NH2:5])(=[NH:4])[CH3:3].[CH3:6][O:7][C:8]1[CH:21]=[CH:20][C:11]([C:12]([CH2:14][C:15](OCC)=[O:16])=O)=[CH:10][CH:9]=1.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[OH:16][C:15]1[CH:14]=[C:12]([C:11]2[CH:10]=[CH:9][C:8]([O:7][CH3:6])=[CH:21][CH:20]=2)[N:5]=[C:2]([CH3:3])[N:4]=1

参加物

実験手順

1.89 g of acetamidine hydrochloride and 4.44 g of etyl paramethoxybenzoylacetate were dissolved in 40 ml of ethanol. After addition of 5.52 g of potassium carbonate, the solution was refluxed with stirring for 8 hours, and then evaporated in vacuo. 5 g of sodium hydroxide was dissolved in 30 ml of water and this was added to the evaporated residue. Add ether, then extract, the aqueous layer was neutralized with acetic acid. The resulting precipitations were filtered off, washed with water and dried. Then 1.1 g of crystals were obtained. Melting point is 270° to 272° C.